At 4 years of age, harpist Manon Le Comte began her musical studies on the recorder, then switched to the harp when she was 11, studying with Dorothy Weldon-Masella at the Conservatoire de musique du Québec in Montreal, where she obtained a Premier prix in 1975. In the summer of 1972 and 1973, she toured with the National Youth Orchestra of Canada.
She has been principal harp with the National Arts Centre Orchestra in Ottawa for nearly 40 years and has been teaching at the Conservatoire de musique de Montréal since 1994. Over the years, she has freelanced mainly in Montreal and Ottawa with a number of orchestras (including the Ottawa Symphony Orchestra, the Montreal Symphony Orchestra, the Orchestre métropolitain, the Société de Musique Contemporaine du Québec et the Nouvel ensemble moderne), in concerts, ballets, operas, shows and recordings (radio, television, records), and occasionally touring in Canada, the United States and Europe. In addition, she has participated in a number of concerts as a chamber musician and soloist with various groups of musicians and several choirs.
She has taught at the Montreal, McGill, Ottawa and Carleton universities. She has also been invited to adjudicate exams and competitions, such as the Canadian Music Competition, the MSO Competition, the Kiwanis Music Festival in Ottawa and the Académie de musique du Québec. In December 2013, she produced her first solo and chamber music CD, "Au fil des cordes", in collaboration with the violonist Olivier Thouin. Then in April 2017 her second CD « Play, sing, dance » came out, this time with the violonist Victor Fournelle-Blain.